BDBM11641 1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyridiniumperchlorate::2,4,6-trimethyl-1-[2-(4-sulfamoylphenyl)ethyl]pyridin-1-ium perchlorate::CHEMBL352535::Compound 10::pyridinium deriv. 10

SMILES Cc1cc(C)[n+](CCc2ccc(cc2)S(N)(=O)=O)c(C)c1

InChI Key InChIKey=UXBCHTZINZNVRG-UHFFFAOYSA-N

Data  28 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 11641   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  14nM ΔG°:  -10.6kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  14nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  14nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 9 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against human carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed